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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
29.09
Human Site:
Y576
Identified Species:
49.23
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
Y576
D
F
F
N
K
G
I
Y
D
I
H
V
G
L
R
Chimpanzee
Pan troglodytes
XP_514393
802
89426
L521
G
L
R
G
V
P
L
L
E
W
E
T
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
Y576
D
F
F
N
K
G
I
Y
D
I
H
V
G
L
R
Dog
Lupus familis
XP_535404
889
99260
Y596
D
F
F
N
K
G
I
Y
D
I
H
V
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
Y577
D
L
F
N
K
G
I
Y
D
V
H
I
G
L
R
Rat
Rattus norvegicus
P51799
803
88712
W522
S
L
L
I
G
A
A
W
G
R
L
F
G
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
Y585
D
F
F
N
K
G
I
Y
D
I
H
V
G
L
R
Chicken
Gallus gallus
XP_417644
868
97172
Y575
D
F
F
N
K
G
I
Y
D
I
H
V
N
L
R
Frog
Xenopus laevis
Q9W701
689
76782
I408
F
G
T
L
A
F
F
I
I
M
K
F
W
M
F
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
Y570
D
F
F
N
R
G
I
Y
D
I
H
I
H
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
S522
A
W
G
R
L
I
G
S
G
L
S
R
L
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
Y480
E
S
T
N
E
I
S
Y
G
L
P
I
M
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G511
E
G
T
Y
A
L
L
G
A
A
S
F
L
G
G
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
P498
S
G
P
S
V
I
I
P
G
A
Y
A
F
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
0
100
100
N.A.
80
6.6
N.A.
100
93.3
0
73.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
20
100
100
N.A.
93.3
20
N.A.
100
93.3
13.3
93.3
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
15
8
8
0
8
15
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
15
0
0
0
8
0
0
0
8
0
8
0
8
0
8
% E
% Phe:
8
43
50
0
0
8
8
0
0
0
0
22
8
8
8
% F
% Gly:
8
22
8
8
8
50
8
8
29
0
0
0
43
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
50
0
8
0
0
% H
% Ile:
0
0
0
8
0
22
58
8
8
43
0
22
0
8
0
% I
% Lys:
0
0
0
0
43
0
0
0
0
0
8
0
0
0
8
% K
% Leu:
0
22
8
8
8
8
15
8
0
15
8
0
15
58
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% M
% Asn:
0
0
0
58
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
0
0
8
0
8
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
8
0
0
0
0
8
0
8
0
0
43
% R
% Ser:
15
8
0
8
0
0
8
8
0
0
15
0
0
0
8
% S
% Thr:
0
0
22
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
0
0
0
0
15
0
0
0
0
8
0
36
0
15
0
% V
% Trp:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
0
% W
% Tyr:
0
0
0
8
0
0
0
58
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _